Proteomics of Biological Systems : Protein Phosphorylation Using Mass Spectrometry Techniques / Bryan M. Ham

By:

Ham, Bryan M

Material type: Text

9781118028964

Subject(s):

DDC classification:

572.62 HamP

Summary: Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies.

List(s) this item appears in: New Arrivals 16-31 October 2025, Vol. 06, Issue 29

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Holdings
Item type	Current library	Collection	Call number	Copy number	Status	Barcode
Books	Indian Institute of Technology Tirupati General Stacks	Chemistry	572.62 HamP (11585) (Browse shelf(Opens below))	Copy 1	Available	11585

Phosphorylation is the addition of a phosphate (PO4) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine whether or not a protein has been correctly modified by the addition of a phosphate group. It also provides a combination of detailed, step-by-step methodology for phosphoproteomic sample preparation, mass spectral instrumental analysis, and data interpretation approaches. Furthermore, it includes the use of bioinformatic Internet tools such as the Blast2GO gene ontology (GO) tool, used to help understand and interpret complex data collected in these studies.

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